How is there not a slam dunk answer to whether this 50+ year old incredibly popular ingredient is ok for us or not?
techwiz137 1 days ago [-]
I can be a case study. I drink over 2 liters of Coca-Cola with aspartame, per day, every day on an empty stomach. With an energy drink, containing aspartame. I am not bragging, it is an addiction.
marcuschong 1 days ago [-]
I also did that for 10+ years. I was actually drinking 3L a day in the last few years.
My BMI and checkups were good. But I was also IFing a lot, having big meals in my eating window and eventually had stomach problems: mild gastritis, hiatal hernia and strong esophagitis. As my family has some history of stomach problems, it's hard to say what was the culprit.
kanbankaren 1 days ago [-]
It is possible you are addicted to the caffeine rather than Diet Coke.
Did you try switching to coffee or caffeine pills?
techwiz137 1 days ago [-]
I like the taste. This is why Monster energy and Coca Cola are my only two drinks. With a hint of 7-up.
maxerickson 23 hours ago [-]
The flavor of Diet Coke only vaguely resembles Coca Cola.
cantrecallmypwd 19 hours ago [-]
My taste buds say Coke Zero better approximates it, although it goes stale in just a few months so cannot sit on the shelf. To me, Diet Coke tastes shallow and like chemicals.
Dwedit 1 days ago [-]
Is it really specific to Aspartame though? What if you switched to a product with a different sweetener, such as Sucralose?
gruez 1 days ago [-]
Limiting yourself to sucralose means paying a premium (it's only used in premium brands) and restricting what brands you can get. If you want "coke" specifically, aspartame is your only choice. They don't make sucralose cokes.
I was hooked on diet coke until one day I decided to take a break, and my tongue felt... weird. It felt slightly fizzy as if my brain was signaling that it was time to drink diet coke. On top of that, I felt lazy for a couple days.
I'm glad I was that self aware because I stopped drinking it everyday. Maybe 1 or two a month.
techwiz137 1 days ago [-]
I attempted this just recently, I went 12+hrs without caffeine intake and I had the worst, headache that wouldn't go away with regular pills. Basically very intense caffeine withdrawal.
snapplebobapple 1 days ago [-]
That lasts for up to a week and then you are through. You should find a quiet week and suffer through once just to prove to yourself you can and to decide whether to consume agaib clean
gruez 1 days ago [-]
>On top of that, I felt lazy for a couple days.
probably because of the caffeine?
D13Fd 1 days ago [-]
Yeah I used to do 2-4 2-liters per day before I gave it up around 12 years ago. I’m hoping that, to the extent it does damage, the effect stops when you stop drinking it.
techwiz137 1 days ago [-]
As far as I've read, our coke zero has a lot of added phosporus or a source of, it seems to somehow bind to calcium leading to perhaps bone loss.
I had an injury I thought was unrelated, but could be. Premature ankle joint wear. On inspection from a CAT scan machine, I was told I seem to have some abrasions on the bone around the damaged area, likely from or similar to osteoporosis and/or osteoarthritis.
kazinator 1 days ago [-]
You could compete in an "Aspartakiad" event. :)
alfiedotwtf 1 days ago [-]
Ok… I’ll be the one to rudely ask, how tall and how much do you weight. I’ll drink 1L of sugar free coke a day, but that’s my definite limit
jpc0 1 days ago [-]
Similar usage... I really do try to drop coke and can go several weeks sometimes but habits are hrd to kick...
189cm and 72kg... For your datapoints.
kanbankaren 1 days ago [-]
I don't know why it is rude to ask. Those are physical attributes that everyone can see IRL.
techwiz137 1 days ago [-]
167cm, and 63-65kg.
theshrike79 1 days ago [-]
It's not a generic thing that's applicable to "everyone". For most(?) people aspartame is just fine. Science is weird with stuff that's not universal, it requires too much studying and narrowing the exact prerequisites and people just give up (or don't get funding).
For others (like me) aspartame is not OK in some cases. I can either drink aspartame and ingest no sugar. Or I can drink sugary drinks. Both are fine.
But if I have both a diet coke AND sugary sweets -> my intestines produce gases that are considered a war crime even by Putin.
No idea why, but it just happens.
n8henrie 1 days ago [-]
Have you read the abstract? I'm a physician with a BS in human nutrition, and at first glance I find it hard to consider anything about that abstract a "slam dunk" for mice and monkeys, far less for humans.
I'm very open to human data that aspartame is bad for humans in reasonable amounts, if you have any, but I haven't seen it.
I'm looking to avoid erythritol these days though.
abtinf 1 days ago [-]
I think you misread the comment you are replying to. They are not saying that the abstract is a slam dunk.
n8henrie 24 hours ago [-]
Yes, I misread -- thank you. I thought it began with "how is this" and not "how is there".
edanm 1 days ago [-]
> I'm looking to avoid erythritol these days though.
Why? My loose sense of the current thinking on this is that erythritol is one of the "safer" alternatives.
n8henrie 23 hours ago [-]
Several studies posted to HN in the last year or so regarding increased risk of blood clots in humans at blood levels similar to those seen at usual amounts of consumption.
loeg 1 days ago [-]
There is!
hedora 1 days ago [-]
There’s strong evidence that all artificial (including “organic non-caloric”) sweeteners disrupt metabolic responses, leading to lethargy and more weight gain than a comparably sweet amount of sugar.
In addition to making you fat, most others have some other bonus side effects like causing cancer, migraines, screwing up gut microbes, etc.
loeg 1 days ago [-]
There is weak or no evidence of this. These products have been widely consumed by hundreds of millions of people over very long timeframes and are broadly very safe. The literature mostly shows the opposite of your weight gain claim.
liamwire 1 days ago [-]
Citation absolutely needed, I’m calling bullshit.
loeg 1 days ago [-]
(In N=6 genetically modified mice fed some huge amount of aspartame.)
readthenotes1 1 days ago [-]
50 mg is over 30 cans of diet coke for most of us.
If we had to consume the amount of aspartame per kilogram these mice did we would have far more serious problems on our hand than insulin resistance
>While an excess of alcohol sugars can cause gastrointestinal distress (e.g., if you overdo it on these you can get diarrhea), in most people they do not cause secretion of insulin from the pancreas due to their distinct chemical structure (see figure of their structures, above).
The same is true for the first group of non-sugar substitute sweeteners I mentioned (e.g., aspartame, saccharin, sucralose), with respect to the lack of insulin response. In addition to studies confirming this, I’ve also documented this in myself for xylitol (my personal favorite), aspartame (Equal), and sucralose (Splenda).
HumanOstrich 1 days ago [-]
False, read TFA. It says the opposite -- there are effects on insulin secretion and resistance for aspartame, saccharin, and sucralose. Only studies funded by the food industry say there is no effect.
edanm 1 days ago [-]
What do you mean, false? The article makes a claim about the outcome of an experiment. He is making a different claim about the outcome of an experiment. What makes his false?
spondylosaurus 1 days ago [-]
Not the aspartame specifically, but the phosphoric acid in (Diet) Coke can be quite soothing if you have a stomachache. Carbonation + phosphoric acid + a Gas-X or two will cure bloating very quickly... and very loudly :P
jvanderbot 1 days ago [-]
Now I have to quit my beloved diet coke as well?
teslabox 2 days ago [-]
Aspartame (1965) was approved by the US FDA in 1974/1981. This is commonly paired with acesulfame-K (1967) to provide sweetness in low-calorie drinks and sodas.
Saccharin (1879) was the first artificial sweetener, followed by cylcamate (1937). Low calorie sodas (Tab, etc) using these sweeteners were introduced in the 1950’s and 1960’s. In the 1980’s diet sodas sweetened with the combination of aspartame and acesulfame-K reached the market.
This is at about the time the obesity epidemic took off. Correlation != causation. I think it’s interesting that the introduction and increased consumption of diet drinks paced the increase in America’s waistlines. U.S. adult obesity rates went from 15% to 30.5% to 41.9% (1980/2000/2020). U.S. childhood obesity went from 5.5% to 13.9% to 19.7% in the same period.
Others have made a case that aspartame, acesulfame-K and sucralose (discovered in 1976, US approval 1998) play a role in the etiology (causation) of the obesity epidemic: people who want to lose a few pounds switched their beverage consumption to artificially sweetened low-calorie drinks. The insulin released by the sweet taste of aspartame lowers people’s blood sugar level, thereby amplifying their hunger. This causes the diet-soda drinker to consume more total calories than if they’d had a HFCS-sweetened beverage.
There are certainly more important contributing factors to “the obesity epidemic”, but I think this is an example of simplistic science: it's technically accurate that low calorie sweeteners have fewer calories than sugar, but they are not that helpful for weight loss. I'd wager it'd be better to consume an 8oz can of HFCS soda than 12oz of 'diet' soda.
Do any of you have any n=1 stories of success or failure using artificial sweeteners? How about herbal sweeteners? If you regularly consume diet sodas, do you combine your diet drink with calories, or is most of your aspartame consumption on an empty stomach?
kace91 1 days ago [-]
Aspartame does not increase insulin, unless I'm not updated on the current scientific consensus.
Also your idea is very american centric, diet sodas are mainstream around the world and most of those countries did not follow the us into the obesity epidemic.
buhfur 1 days ago [-]
Now i'm no health specialist but from what I gathered online , it's still a debated subject.
HumanOstrich 1 days ago [-]
You are definitely not updated on current scientific research. TFA discusses this.
throw034248 2 days ago [-]
I'm not overweight, but I observed the following:
- All artificial sweeteners when consumed on empty-stomach, causes very strong feelings of hunger in a short time. My guess is that this can more than cancel out the reduced calorie content.
- Sucralose gives me headaches.
layer8 1 days ago [-]
They do neither for me.
cantrecallmypwd 19 hours ago [-]
Might be psychosomatic or unrelated to the sweetener.
Drinks containing caffeine tend to lead to mild dehydration and caffeine withdrawal headaches.
riku_iki 1 days ago [-]
I personally don't observe this
profsummergig 1 days ago [-]
I started drinking too much alcohol during the lockdown era.
I experimented with non-alcoholic mocktails. The one that works for me is diet cola + milk in equal proportions. Somehow provides the combination of richness/creaminess, sweetness, bitterness that replaces the feeling of drinking Irish cream.
Diet cola contains aspartame. Anyone know if there's a safer non-sugar version of or alternative to diet cola that I could use instead?
kelseyfrog 1 days ago [-]
Pilk? In all earnestness, I thought that was a joke drink.
downrightmike 2 days ago [-]
I think the link between diet sodas is more "I am not drinking sugar, so I can eat more" Not so much, "diet soda makes you fat directly"
mrandish 1 days ago [-]
> Do any of you have any n=1 stories of success or failure using artificial sweeteners?
My N=1 is that I've always liked Diet Cola drinks - a lot. I easily drink more than a couple liters a day and have since at least 1990. I have my own soda fountain at home (along with a flake ice machine). I was significantly overweight for about two decades. I'd tried a lot of different weight loss programs over the years including medically supervised. I approached each diet very diligently and put in a lot of effort - yet none ever worked long-term for me. I'd lose 10 or 20 pounds over a few months but would put it back on. I was always back where I started (or worse) in less than six months.
About seven years ago I decided to try keto. It was definitely the hardest, weirdest and strictest of any diet I'd tried but I did the entire program very diligently - just like the others. Keto worked extremely well for me, where nothing else had. The first 5-6 weeks was hard - not because I was hungry but just due to the degree of change, new things to learn and the rigorous ingredient tracking. All the other diets were much easier but I was constantly hungry. On keto it was the opposite. After the first three days, I was never hungry on keto. The challenge in keto was changing habits, learning new patterns and missing the flavors of familiar carb-heavy foods. But that only lasted about six weeks. After that my palette had been retrained and I didn't miss carb-heavy "comfort foods". I also had gotten used to the new patterns and it didn't take much extra effort or thought. Over the next 8 months I lost close to a hundred pounds, putting me back at a weight I hadn't seen since high school. I went from size 42 pants to 32 and I had abs! I lost weight so fast in the first three months, I heard some people at work suspected I had cancer or something.
To answer your question, I never changed my very heavy Diet Coke consumption during any of this. If anything, I increased it. And I've now stayed at my ideal weight for the last seven years. I stayed strict keto for the first couple years but now I'm not as strict although definitely still low carb by choice - because I feel better mentally, emotionally and physically on low-carb and because I now prefer these new foods and flavors. Doing keto helped put me in control of my weight and calorie intake through managing my blood sugar - and for me that was the key difference and a major revelation. I'm still never hungry and I can easily manage my intake and weight. If I creep up five pounds, I make a minor adjustment and it's gone in a few days.
However, I don't think keto will necessarily do the same for everyone. I've learned different people have different metabolisms as well as different preferences and ability to adapt to different changes. Strict carb management worked long term for me and Aspartame wasn't a barrier. The other counter-intuitive thing about my weight loss experience was I found early on that exercising did make me hungrier - so I stopped all exercise. While I've never been one for exercise or working out, during the 8 months I lost all the weight I became even more sedentary. I'm not suggesting that to anyone else, of course. I'm just sharing it as an example of finding what works for your metabolism, lifestyle and preferences. Interestingly, after I lost all the weight I found I started liking exercise more than I ever had and continue to today, seven years later. The typical advice is "Cut calories and hit the gym." What worked for me was "Cut carbs and hit the couch." My first week on keto I dropped almost all carbs but actually increased my calories (mostly in meat and cheeses). Once I'd weaned myself off carbs and had control of my blood sugar, cutting calories wasn't just easier - it sort of took care of itself. The whole 8 months I just counted carbs and stayed under 20 a day, while eating as much as I wanted. Without carbs driving my blood sugar and hunger, "as much as I wanted" to feel full all the time turned out to be a lot less calories. The key with the keto strategy is it only works if you execute it rigorously. Cheat all you want on calories but if you "cheat" on the carbs and go over 20g/day, even a little, you'll not only fail - you'll put on even more weight than before. I think a lot of people see that as a major downside but, oddly, for me the "all or nothing" aspect of keto turned out to be an unexpectedly helpful "feature".
spondylosaurus 1 days ago [-]
My partner's lost a fair amount of weight on GLP-1 drugs and continues to drink Diet Coke like a fiend, and same thing, it doesn't seem to hurt their progress.
Very curious about that soda fountain and flake ice machine though...
This just begs the next "why". Why are people eating more now?
Such a significant behavior change across a large population is not well explained by "we just did".
I'm not sure fast food consumption or huge portion sizes is a great explanation. If fast food is the problem, why does that matter if it just comes down to calories? As for larger portion sizes, would even larger portions make us continue eating? Would tiny portion sizes make us all deadly malnourished?
bobthepanda 2 days ago [-]
I wonder if it's correlated with cars.
We do know that walking rates, across the country, have fallen significantly. In 1969, approximately 50% of children walked or bicycled to school, with approximately 87% of children living within one mile of school walking or bicycling. Today, fewer than 15% of schoolchildren walk or bicycle to school. And we see this generally across the board, where for the most part driving to work alone dominates commute habits. If the only walking you do is from the door to the car, you are not getting much routine physical activity.
This would also actually well correlate with the rate of fast food consumption, since it's primarily car-centric, and is more car-centric than other types of eating out.
I also don't think it's really any sort of secret that fast food companies like return customers and engineer the types of food that become addictive. There is a book called the Dorito Effect which theorizes that not only has artificial food become more flavorful over time, but that our industrial scale food production has made the base products less flavorful in favor of prettier or hardier varietals.
Food got way, way cheaper, including and especially convenient (ready to eat) food. Plus a race between companies selling that food to optimize flavor and marketing strategies for maximum sales, which, at some point, had to start meaning “more eating”, not “more eating this instead of something else” otherwise line could not go up.
Guzba 1 days ago [-]
With this in mind, is the real cause "calories in, calories out" or "optimized flavor and marketing strategies"?
alabastervlog 1 days ago [-]
The reason a person gains weight is CICO.
The reason a population gains weight is way more complicated and probably best short-handed as “social”. Moving to America typically makes people gain weight. Leaving it leads to weight loss. If you’re trying to fix an overweight population, you need to look at lots and lots of things and, demonstrably (as in: the science is pretty clear), telling people to simply eat less and even very expensive high-touch interventions aimed at diet correction don’t work. Wrong tree to bark up, your solution lies elsewhere—or, probably, several elsewheres.
(But drugs might work!)
loeg 1 days ago [-]
Potato, potato. CICO is just physics, but "optimized flavor and marketing strategies" has had impact on the "CI" side of the equation.
Guzba 1 days ago [-]
It seems very different and critically important. Would we have a current obesity epidemic without "optimized flavor and marketing strategies"? Because if we would not, then that is the true cause and of fundamental public health importance.
If we would have an obesity epidemic even without "optimized flavor and marketing strategies", then it is totally irrelevant.
loeg 1 days ago [-]
Yes and no. I think there are two levers on the CI side of the equation and only one of them is hyper-palatability (optimized flavor); the other is simply cost. Food costs have fallen sharply, and that contributes to over-feeding. Hyper-palatability also contributes. It's not irrelevant, but not the only factor.
esskay 1 days ago [-]
> This just begs the next "why". Why are people eating more now?
Have you been in a US supermarket? It's absolutely nuts and I don't think many Americans realise it.
To be bombarded with monumentally huge portions of everything is just a recipe for...well....the situation the US is in. Theres not many other countries that have whole food groups focused on cramming in as much peanut butter, jelly, marshmallow, chocolate, or whatever other high fructose corn syrup crap is being used.
Massive slices of cake prepackaged and ready to eat? Yeah why not.
50 different coffee syrup flavors? Yeah go for it.
How about a lovely massive bottle of sugary drink to wash it down? Just one? No no have a crate of 20 of the things.
Just for a comparison, look up candy on the Walmart site. Now do it on Tesco UK. Next, try the bakery, or hell even the meat isle, somehow the exact same product ends up being significantly worse for you in the US.
sevensor 20 hours ago [-]
I didn’t fully grasp how poorly our US bread approximates the real thing until I visited Europe. It’s weirdly spongy and candy sweet, and that’s the “healthy” bread in the bread aisle. Our food culture is just kind of gross most of the time, and the ersatz health food is some of the worst, as it’s been punched up with loads of organic cane juice or pear juice concentrate. Or celery juice if it’s a product that wants to claim not to have added nitrates. And, it should go without saying, truckloads of salt.
Guzba 1 days ago [-]
The orthodox reason for why people are overweight is calories in, calories out. Does it matter if those calories are a prepackaged cake or candy? In the end it is just calories.
Would gratuitously large steaks in the meat section and huge rotisserie turkeys instead of chicken at Costco produce the same result?
It seems strange to pick on certain types of foods unless believe those foods are the cause of obesity instead of just eating too many calories of any kind.
If you think cookies and candy are bad but other things are not, why? Is it that they are easier to over-eat? If so, how does that compound over time, given humans are trying to maintain homeostasis which includes a healthy set weight via satiety. Exercise induces more calorie consumption later. Over calorie consumption also induces lower consumption later. This seem like relevant factors.
colingauvin 1 days ago [-]
This is an oversimplification.
>Does it matter if those calories are a prepackaged cake or candy? In the end it is just calories.
In the end it's a complex, poorly understood network of hormones and brain chemistry. Human action is mostly downstream of that.
Guzba 1 days ago [-]
I agree, however for some reason calories in calories out is generally unquestioned among people I know personally.
ein0p 1 days ago [-]
It is, of course, not as easy as calories in / calories out, although the "Twinkies experiment" proved that you can in fact lose weight via caloric restriction alone. For any kind of "normal" diet insulin plays a massive role in obesity. And that bag of candy will absolutely send it to the stratosphere, especially if you consume sweets frequently. Buy a continuous glucose monitor (it's now available OTC via Stelo), and see for yourself. That's what I did.
Guzba 1 days ago [-]
I am aware of this, I am more trying to get those that really believe it is as simple as calories in calories out to break free from that Plato-ey over-simplified explanation.
nobodyandproud 1 days ago [-]
Food designed to circumvent the sensation of cloying or satiation.
Also, eating more in isolation and without talking.
Guzba 1 days ago [-]
Food design does seem like a higher potential explanation than many others offered.
denkmoon 1 days ago [-]
The proportion of households with a person with time and energy to prepare a healthy home cooked meal has diminished. We have sacrificed domestic life on the altar of profit.
homebrewer 1 days ago [-]
It really doesn't have to take more than 10-15 minutes per day in total, you just have to be aware of what you're doing. I know several examples — including myself — who eat healthy food on a budget and spend very little time doing it. We had our problems with American-style food when it appeared and became popular (I had a BMI of 30.5 for several years and blamed everything but myself), but quickly self corrected before real damage was done.
Guzba 1 days ago [-]
If healthy home cooked meals are better, why is that? This is a non-answer.
It must be something about the ingredients (invalidating calorie theory) or it must be lower calorie (invalidating ingredient theory).
profsummergig 1 days ago [-]
Why does capitalism not make people fat in Japan, France, Italy and Spain?
redwall_hp 1 days ago [-]
Japan's easy: only about 1-in-3 households in Tokyo (and presumably the other large cities, where the majority of people live, are similar) own a car. People walk and take trains to work or to go shopping or eat out. A half hour of walking can burn upwards of 100 calories.
The typical diet is also relatively lower in bread (processed carbohydrates...with unnecessary added sugar in the US) and higher in protein. That combination is typical of any structured diet designed around controlling weight gain, such as Weight Watchers.
Fast food is also different. International menus have different items and different sizes. I've seen people express shock about the existence of things like the Triple Baconator or US soda sizes. Drinking a 32 oz of sugar-filled soda is an easy 350 calories right there, and a disturbing number of Americans "don't like water."
Konbini and ramen/soba shops also exist, so there are even more convenient alternatives to western fast food, which are often healthier in the typical portions.
profsummergig 1 days ago [-]
> diet is also relatively lower in bread
I've wondered about about carb substitution. The rice, and the wheat noodles, why are they healthier? (I can understand rice somewhat: it's less processed, by certain definitions.)
Jensson 1 days ago [-]
> and the wheat noodles
Buckwheat is not wheat, soba noodles are based on buckwheat.
Not sure how large fraction of all noodles they eat are that though. Feels like there is something related to additives and other things that makes people eat more.
ndsipa_pomu 1 days ago [-]
> Buckwheat is not wheat, soba noodles are based on buckwheat.
Whilst you're correct about buckwheat, just about all soba noodles that I've seen here in the UK are predominantly wheat based (I'm gluten sensitive, so have read a lot of product labels).
When looking for gluten free noodles in Asian supermarkets, I've only really found ones that are rice based with some rarer sweet potato vermicelli varieties.
Edit: after a brief search, I have found some Clearspring 100% buckwheat noodles which I shall have to find and buy. They also sell the more usual wheat and buckwheat version of Soba noodles.
ein0p 1 days ago [-]
Probably slower absorption. Bread really peaks blood glucose, and therefore insulin.
ein0p 1 days ago [-]
They have much smaller portions across the board. Their "venti" Starbucks drink is what we call "small" in the US, and our "venti" is simply not available. Might even be smaller than small, it sure seemed like it.
tulio_ribeiro 2 days ago [-]
Sweeteners are processed food. Timeline shows more processed food hitting the market, period. Obesity rises. Coincidence? Doubt it.
It's not just the sweetener itself. It's the whole shift. More processed crap in everything, sweeteners included. Cheaper, easier, engineered to be addictive. That's the real change that lines up with the weight gain.
Focusing just on sweeteners is missing the point. They're just one piece of the bigger processed food takeover. That's the simpler, more likely explanation.
> Broadly speaking, we eat a lot more than we used to: The average American consumed 2,481 calories a day in 2010, about 23% more than in 1970. That’s more than most adults need to maintain their current weight
edanm 1 days ago [-]
> Calorie intake is up. Don't overcomplicate it.
You're doing the opposite - oversimplifying it. Why is calorie intake up is a legitimate, important question.
brandonmenc 1 days ago [-]
Because calories are cheaper now, thanks in large part to low cost, energy dense vegetable oils.
When people can get more calories per dollar they will eat more calories.
edanm 23 hours ago [-]
Totally might be the case. I'm not sure, but I think I've seen good reasons to think this doesn't exactly line up though - increased wealth in different countries didn't match exactly, timeline wise.
But I'm far from an expert
sandworm101 1 days ago [-]
"Processed food" is a term without meaning. Amost all food is processed. Yogert is processed. Bread is processed. Steak is processed. Even raw fruit is arguably processed as it is picked before being ripe to eat and then subject to an optimized ripening process (google the science behind banana shipping). All foods are either cooked or mechanically/chemically processed prior to consumption. We are aguably unable to survive on unprocessed food. Short of biting into a whole head of lettuce, or into the side of a live animal, one cannot avoid processed foods. Washing/cooking has saved us from all manner of paracites. The people who eat raw/unprocceed foods are the ones who wind up with worms in thier brains. What matters for health is the degree of processing that does not add nutrition or safety, with every pundit picking thier own arbitrary point somewhere between a healthy chopped salad and a microwaved hot pocket. Imho, just avoid anything with added sugar or salt.
atombender 1 days ago [-]
"Ultraprocessed" is arguably the more important term. While also formally defined, a rule of thumb is that if the average person can't make it in their kitchen, it's ultraprocessed. These are chemicals chemicals that are used to emulsify or stabilize ingredients, preservatives, and chemicals used to improve mouthfeel and texture: like lecithin, polysorbate, sodium benzoate, maltodextrin, partially hydrogenated oils, sodium phosphates, etc. — there are tons of them. Some of them have been implicated in causing gut inflammation.
loeg 1 days ago [-]
"Ultra-processed" is just a retcon'd term circularly defined as any calorie dense, low satiety food you already have reason to believe is unhealthy.
Yes, really. Nova's definition is exactly what I'm describing earlier. Here is their own definition, from the wiki you linked:
> There is no simple definition of UPF, but they are generally understood to be an industrial creation derived from natural food or synthesized from other organic compounds. The resulting products are designed to be highly profitable, convenient, and hyperpalatable, often through food additives such as preservatives, colourings, and flavourings.
> This is at about the time the obesity epidemic took off. Correlation != causation.
Average heights continued increasing through the 1980s. This suggests that a not insignificant chunk of the population was still in caloric deprivation until the 1990s. You can't get obesity while lots of people are still continuously hungry. For this one, correlation probably is causation.
In addition, smoking bans took off in the 1990s. Nicotine is a noted appetite suppressant. Correlation might be causation. You may be trading the problems of smoking for the problems of obesity--probably a decent trade.
catigula 1 days ago [-]
Doubtful.
Smokers only gain a handful of pounds when they stop on average.
bsder 1 days ago [-]
You're gonna have to quote something stronger about that.
In college, I knew a lot of girls who took up smoking to help get rid of the freshman fifteen. It seemed to work for the most part.
pyb 1 days ago [-]
... in mice
layer8 1 days ago [-]
Mostly, yes: “in the monkey model, owing to technical difficulties and feasibilities, our current work did not include the impact of APM on atherosclerosis”.
Separo 2 days ago [-]
Coke Zero
Rendered at 11:06:47 GMT+0000 (Coordinated Universal Time) with Vercel.
My BMI and checkups were good. But I was also IFing a lot, having big meals in my eating window and eventually had stomach problems: mild gastritis, hiatal hernia and strong esophagitis. As my family has some history of stomach problems, it's hard to say what was the culprit.
Did you try switching to coffee or caffeine pills?
https://www.coca-cola.com/us/en/brands/coca-cola/products/ze...
>CARBONATED WATER, CARAMEL COLOR, PHOSPHORIC ACID, ASPARTAME, POTASSIUM BENZOATE (TO PROTECT TASTE), NATURAL FLAVORS, POTASSIUM CITRATE, ACESULFAME POTASSIUM, CAFFEINE, STEVIA EXTRACT.
Not sure how stevia got on there. The zero caffeine version (also on that list) doesn't have it. Nor does Amazon's listing
https://www.amazon.com/Coca-Cola-Zero-Sugar-Fridgepack-Pack/...
I'm glad I was that self aware because I stopped drinking it everyday. Maybe 1 or two a month.
probably because of the caffeine?
I had an injury I thought was unrelated, but could be. Premature ankle joint wear. On inspection from a CAT scan machine, I was told I seem to have some abrasions on the bone around the damaged area, likely from or similar to osteoporosis and/or osteoarthritis.
189cm and 72kg... For your datapoints.
For others (like me) aspartame is not OK in some cases. I can either drink aspartame and ingest no sugar. Or I can drink sugary drinks. Both are fine.
But if I have both a diet coke AND sugary sweets -> my intestines produce gases that are considered a war crime even by Putin.
No idea why, but it just happens.
I'm very open to human data that aspartame is bad for humans in reasonable amounts, if you have any, but I haven't seen it.
I'm looking to avoid erythritol these days though.
Why? My loose sense of the current thinking on this is that erythritol is one of the "safer" alternatives.
In addition to making you fat, most others have some other bonus side effects like causing cancer, migraines, screwing up gut microbes, etc.
If we had to consume the amount of aspartame per kilogram these mice did we would have far more serious problems on our hand than insulin resistance
https://peterattiamd.com/what-are-the-side-effects-of-aspart...
>While an excess of alcohol sugars can cause gastrointestinal distress (e.g., if you overdo it on these you can get diarrhea), in most people they do not cause secretion of insulin from the pancreas due to their distinct chemical structure (see figure of their structures, above).
The same is true for the first group of non-sugar substitute sweeteners I mentioned (e.g., aspartame, saccharin, sucralose), with respect to the lack of insulin response. In addition to studies confirming this, I’ve also documented this in myself for xylitol (my personal favorite), aspartame (Equal), and sucralose (Splenda).
Saccharin (1879) was the first artificial sweetener, followed by cylcamate (1937). Low calorie sodas (Tab, etc) using these sweeteners were introduced in the 1950’s and 1960’s. In the 1980’s diet sodas sweetened with the combination of aspartame and acesulfame-K reached the market.
This is at about the time the obesity epidemic took off. Correlation != causation. I think it’s interesting that the introduction and increased consumption of diet drinks paced the increase in America’s waistlines. U.S. adult obesity rates went from 15% to 30.5% to 41.9% (1980/2000/2020). U.S. childhood obesity went from 5.5% to 13.9% to 19.7% in the same period.
Others have made a case that aspartame, acesulfame-K and sucralose (discovered in 1976, US approval 1998) play a role in the etiology (causation) of the obesity epidemic: people who want to lose a few pounds switched their beverage consumption to artificially sweetened low-calorie drinks. The insulin released by the sweet taste of aspartame lowers people’s blood sugar level, thereby amplifying their hunger. This causes the diet-soda drinker to consume more total calories than if they’d had a HFCS-sweetened beverage.
There are certainly more important contributing factors to “the obesity epidemic”, but I think this is an example of simplistic science: it's technically accurate that low calorie sweeteners have fewer calories than sugar, but they are not that helpful for weight loss. I'd wager it'd be better to consume an 8oz can of HFCS soda than 12oz of 'diet' soda.
Do any of you have any n=1 stories of success or failure using artificial sweeteners? How about herbal sweeteners? If you regularly consume diet sodas, do you combine your diet drink with calories, or is most of your aspartame consumption on an empty stomach?
Also your idea is very american centric, diet sodas are mainstream around the world and most of those countries did not follow the us into the obesity epidemic.
- All artificial sweeteners when consumed on empty-stomach, causes very strong feelings of hunger in a short time. My guess is that this can more than cancel out the reduced calorie content.
- Sucralose gives me headaches.
Drinks containing caffeine tend to lead to mild dehydration and caffeine withdrawal headaches.
I experimented with non-alcoholic mocktails. The one that works for me is diet cola + milk in equal proportions. Somehow provides the combination of richness/creaminess, sweetness, bitterness that replaces the feeling of drinking Irish cream.
Diet cola contains aspartame. Anyone know if there's a safer non-sugar version of or alternative to diet cola that I could use instead?
My N=1 is that I've always liked Diet Cola drinks - a lot. I easily drink more than a couple liters a day and have since at least 1990. I have my own soda fountain at home (along with a flake ice machine). I was significantly overweight for about two decades. I'd tried a lot of different weight loss programs over the years including medically supervised. I approached each diet very diligently and put in a lot of effort - yet none ever worked long-term for me. I'd lose 10 or 20 pounds over a few months but would put it back on. I was always back where I started (or worse) in less than six months.
About seven years ago I decided to try keto. It was definitely the hardest, weirdest and strictest of any diet I'd tried but I did the entire program very diligently - just like the others. Keto worked extremely well for me, where nothing else had. The first 5-6 weeks was hard - not because I was hungry but just due to the degree of change, new things to learn and the rigorous ingredient tracking. All the other diets were much easier but I was constantly hungry. On keto it was the opposite. After the first three days, I was never hungry on keto. The challenge in keto was changing habits, learning new patterns and missing the flavors of familiar carb-heavy foods. But that only lasted about six weeks. After that my palette had been retrained and I didn't miss carb-heavy "comfort foods". I also had gotten used to the new patterns and it didn't take much extra effort or thought. Over the next 8 months I lost close to a hundred pounds, putting me back at a weight I hadn't seen since high school. I went from size 42 pants to 32 and I had abs! I lost weight so fast in the first three months, I heard some people at work suspected I had cancer or something.
To answer your question, I never changed my very heavy Diet Coke consumption during any of this. If anything, I increased it. And I've now stayed at my ideal weight for the last seven years. I stayed strict keto for the first couple years but now I'm not as strict although definitely still low carb by choice - because I feel better mentally, emotionally and physically on low-carb and because I now prefer these new foods and flavors. Doing keto helped put me in control of my weight and calorie intake through managing my blood sugar - and for me that was the key difference and a major revelation. I'm still never hungry and I can easily manage my intake and weight. If I creep up five pounds, I make a minor adjustment and it's gone in a few days.
However, I don't think keto will necessarily do the same for everyone. I've learned different people have different metabolisms as well as different preferences and ability to adapt to different changes. Strict carb management worked long term for me and Aspartame wasn't a barrier. The other counter-intuitive thing about my weight loss experience was I found early on that exercising did make me hungrier - so I stopped all exercise. While I've never been one for exercise or working out, during the 8 months I lost all the weight I became even more sedentary. I'm not suggesting that to anyone else, of course. I'm just sharing it as an example of finding what works for your metabolism, lifestyle and preferences. Interestingly, after I lost all the weight I found I started liking exercise more than I ever had and continue to today, seven years later. The typical advice is "Cut calories and hit the gym." What worked for me was "Cut carbs and hit the couch." My first week on keto I dropped almost all carbs but actually increased my calories (mostly in meat and cheeses). Once I'd weaned myself off carbs and had control of my blood sugar, cutting calories wasn't just easier - it sort of took care of itself. The whole 8 months I just counted carbs and stayed under 20 a day, while eating as much as I wanted. Without carbs driving my blood sugar and hunger, "as much as I wanted" to feel full all the time turned out to be a lot less calories. The key with the keto strategy is it only works if you execute it rigorously. Cheat all you want on calories but if you "cheat" on the carbs and go over 20g/day, even a little, you'll not only fail - you'll put on even more weight than before. I think a lot of people see that as a major downside but, oddly, for me the "all or nothing" aspect of keto turned out to be an unexpectedly helpful "feature".
Very curious about that soda fountain and flake ice machine though...
It's not "aspartame". It's eating out twice as much as we did in early 70s [1], rise of fast food consumption, and huge portion sizes.
[1] https://www.ers.usda.gov/data-products/food-consumption-nutr...
Such a significant behavior change across a large population is not well explained by "we just did".
I'm not sure fast food consumption or huge portion sizes is a great explanation. If fast food is the problem, why does that matter if it just comes down to calories? As for larger portion sizes, would even larger portions make us continue eating? Would tiny portion sizes make us all deadly malnourished?
We do know that walking rates, across the country, have fallen significantly. In 1969, approximately 50% of children walked or bicycled to school, with approximately 87% of children living within one mile of school walking or bicycling. Today, fewer than 15% of schoolchildren walk or bicycle to school. And we see this generally across the board, where for the most part driving to work alone dominates commute habits. If the only walking you do is from the door to the car, you are not getting much routine physical activity.
This would also actually well correlate with the rate of fast food consumption, since it's primarily car-centric, and is more car-centric than other types of eating out.
https://www.saferoutespartnership.org/sites/default/files/pd...
---
I also don't think it's really any sort of secret that fast food companies like return customers and engineer the types of food that become addictive. There is a book called the Dorito Effect which theorizes that not only has artificial food become more flavorful over time, but that our industrial scale food production has made the base products less flavorful in favor of prettier or hardier varietals.
https://foodcrumbles.com/the-dorito-effect-book-review/
The reason a population gains weight is way more complicated and probably best short-handed as “social”. Moving to America typically makes people gain weight. Leaving it leads to weight loss. If you’re trying to fix an overweight population, you need to look at lots and lots of things and, demonstrably (as in: the science is pretty clear), telling people to simply eat less and even very expensive high-touch interventions aimed at diet correction don’t work. Wrong tree to bark up, your solution lies elsewhere—or, probably, several elsewheres.
(But drugs might work!)
If we would have an obesity epidemic even without "optimized flavor and marketing strategies", then it is totally irrelevant.
Have you been in a US supermarket? It's absolutely nuts and I don't think many Americans realise it.
To be bombarded with monumentally huge portions of everything is just a recipe for...well....the situation the US is in. Theres not many other countries that have whole food groups focused on cramming in as much peanut butter, jelly, marshmallow, chocolate, or whatever other high fructose corn syrup crap is being used.
Massive slices of cake prepackaged and ready to eat? Yeah why not. 50 different coffee syrup flavors? Yeah go for it. How about a lovely massive bottle of sugary drink to wash it down? Just one? No no have a crate of 20 of the things.
Just for a comparison, look up candy on the Walmart site. Now do it on Tesco UK. Next, try the bakery, or hell even the meat isle, somehow the exact same product ends up being significantly worse for you in the US.
Would gratuitously large steaks in the meat section and huge rotisserie turkeys instead of chicken at Costco produce the same result?
It seems strange to pick on certain types of foods unless believe those foods are the cause of obesity instead of just eating too many calories of any kind.
If you think cookies and candy are bad but other things are not, why? Is it that they are easier to over-eat? If so, how does that compound over time, given humans are trying to maintain homeostasis which includes a healthy set weight via satiety. Exercise induces more calorie consumption later. Over calorie consumption also induces lower consumption later. This seem like relevant factors.
>Does it matter if those calories are a prepackaged cake or candy? In the end it is just calories.
In the end it's a complex, poorly understood network of hormones and brain chemistry. Human action is mostly downstream of that.
Also, eating more in isolation and without talking.
It must be something about the ingredients (invalidating calorie theory) or it must be lower calorie (invalidating ingredient theory).
The typical diet is also relatively lower in bread (processed carbohydrates...with unnecessary added sugar in the US) and higher in protein. That combination is typical of any structured diet designed around controlling weight gain, such as Weight Watchers.
Fast food is also different. International menus have different items and different sizes. I've seen people express shock about the existence of things like the Triple Baconator or US soda sizes. Drinking a 32 oz of sugar-filled soda is an easy 350 calories right there, and a disturbing number of Americans "don't like water."
Konbini and ramen/soba shops also exist, so there are even more convenient alternatives to western fast food, which are often healthier in the typical portions.
I've wondered about about carb substitution. The rice, and the wheat noodles, why are they healthier? (I can understand rice somewhat: it's less processed, by certain definitions.)
Buckwheat is not wheat, soba noodles are based on buckwheat.
Not sure how large fraction of all noodles they eat are that though. Feels like there is something related to additives and other things that makes people eat more.
Whilst you're correct about buckwheat, just about all soba noodles that I've seen here in the UK are predominantly wheat based (I'm gluten sensitive, so have read a lot of product labels).
When looking for gluten free noodles in Asian supermarkets, I've only really found ones that are rice based with some rarer sweet potato vermicelli varieties.
Edit: after a brief search, I have found some Clearspring 100% buckwheat noodles which I shall have to find and buy. They also sell the more usual wheat and buckwheat version of Soba noodles.
It's not just the sweetener itself. It's the whole shift. More processed crap in everything, sweeteners included. Cheaper, easier, engineered to be addictive. That's the real change that lines up with the weight gain.
Focusing just on sweeteners is missing the point. They're just one piece of the bigger processed food takeover. That's the simpler, more likely explanation.
From 2016:
https://www.pewresearch.org/short-reads/2016/12/13/whats-on-...
> Broadly speaking, we eat a lot more than we used to: The average American consumed 2,481 calories a day in 2010, about 23% more than in 1970. That’s more than most adults need to maintain their current weight
You're doing the opposite - oversimplifying it. Why is calorie intake up is a legitimate, important question.
When people can get more calories per dollar they will eat more calories.
But I'm far from an expert
> There is no simple definition of UPF, but they are generally understood to be an industrial creation derived from natural food or synthesized from other organic compounds. The resulting products are designed to be highly profitable, convenient, and hyperpalatable, often through food additives such as preservatives, colourings, and flavourings.
https://en.wikipedia.org/wiki/Ultra-processed_food
Average heights continued increasing through the 1980s. This suggests that a not insignificant chunk of the population was still in caloric deprivation until the 1990s. You can't get obesity while lots of people are still continuously hungry. For this one, correlation probably is causation.
In addition, smoking bans took off in the 1990s. Nicotine is a noted appetite suppressant. Correlation might be causation. You may be trading the problems of smoking for the problems of obesity--probably a decent trade.
Smokers only gain a handful of pounds when they stop on average.
In college, I knew a lot of girls who took up smoking to help get rid of the freshman fifteen. It seemed to work for the most part.