Always love reading Derek Lowe's writings. One thing confused me, though:

>These authors find that it has potent activity against the ion channel TRPM8, and that goes for other 7-nitro compounds in this series as well.

But later states

>For one thing, the other benzodiazepines aren’t much use; clonazepam really stands out on its own.

Wouldn't another 7-nitro compound also work? Flunitrazepam/Rohypnol, for example? A little bit of research shows it actually might[1].

[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC13426060/