To get a job at our company take three pills of brainOzempic every day to maximize productivity.
We have our NeuroLinkBrain Implant plugin to AI agent , so that you can vibe code 24/7 . To maximize shareholder value.
Uptrenda 32 seconds ago [-]
I know you're joking but I saw a company that had similar policies like fasting and stuff like that to improve productivity. They seemed to take it pretty seriously...
anakaine 29 minutes ago [-]
I reckon I'll buy some landscaping machinery and a truck before I ever sign up for that distopian nightmare. At least sound ordinance would prevent 24/7 operation.
bowmessage 20 minutes ago [-]
No more sound ordinance, just install Neuralink and receive free auto-mute during sleeping hours.
seeknotfind 29 minutes ago [-]
Is this supposed to be scary or amazing?
alimhaq 19 minutes ago [-]
Your comment is probably the most disturbing thing I’ve ever read on this website
rc5150 10 minutes ago [-]
I dunno, there's been a whole lot of fascist bootlicking going on lately under the guise of good faith discussion. That's pretty disturbing to me.
vhcr 20 minutes ago [-]
Isn't this already happening with ADHD drugs?
yuye 12 minutes ago [-]
A lot of people with ADHD that have success with medication can tell you that it's not just about work.
It also helps with non-work stuff that's just not fun to do, such as chores or filing your taxes. It even helps you stick with hobbies you actually enjoy but your brain gets bored of.
chocrates 9 minutes ago [-]
Don't tell me psychiatrist but I take my addon Ritalin at night so I can play games or read a book. I just can't do it without it
rc5150 12 minutes ago [-]
on the recreational level, maybe, but from a therapeutic perspective for people who actually benefit from its prescribed use its absolutely game-changing to live a life without (or with mitigated) executive dysfunction.
derefr 25 minutes ago [-]
My partner has had idiopathic hypersomnia (sleeps 12 hours most days, as much as 18 hours some days) for a few years now, and so far nothing we’ve tried has worked without awful side effects (e.g. constant heart palpitations and panic attacks.)
I had been looking into orexin agonists (along with other things like H3 autoreceptor antagonists) back when they were just a concept. It’s good to see them finally reaching commercialization. Although they’re not approved by our own (Canadian) regulatory body quite yet.
Now that they’re approved in the US, though, I’m looking very much forward to seeing how these drugs perform in off-label-ish treatment of the various other sleep disorders that I’m sure clinicians will now begin throwing them at.
chasebank 9 minutes ago [-]
Have they tried GHB? I know it's used in narcolepsy patients with great success. If you "microdose" it, it's also one of the best drugs on the planet. Slippery slope, though.
fedpost 29 minutes ago [-]
Well, they're filming the next season of black mirror right now, it's probably not too late to throw this one in there.
SoupBread 1 hours ago [-]
It sounds like is a genuine treatment for those who suffer from narcolepsy, and everything else is merely speculative and has seem pretty bad side-effects.
bitexploder 58 minutes ago [-]
There is evidence that some forms of ADHD are effectively just the brain falling asleep rapidly and then waking up. This form cam be attenuated with norepinephrine reuptake inhibitor alone. Presents with ADHD like symptoms. But it’s a new thing most likely. Called “Cognitive Disengagement Syndrome”.
> IMO the much more likely explanation is that the brain uses contrastive learning somewhere. [...] Instead of using calculus and outer products to calculate derivatives, you feed real data and false data forward through the network and each neuron tracks and trains on the difference.
Kinrany 46 minutes ago [-]
Separately, do I understand the idea correctly:
- when learning on the real examples, just propagate forward
- when learning on the fake examples, first generate them by propagating white noise backward
inigyou 24 minutes ago [-]
That's a technique that was tried in machine learning and worked (although obviously not optimally or we'd all be using it by now) and then we hypothesised that animal brains use it because it would explain sleep.
Kinrany 48 minutes ago [-]
I'm curious if there is an explanation for it not being more common to sleep like dolphins do, small parts of the brain at a time.
fishfasell 1 hours ago [-]
Despite the stigma surrounding semaglutide, its impact across various health conditions has been remarkable. Bringing that same level of innovation to cognitive disorders could be truly transformative for society
fennec-posix 2 hours ago [-]
If this means I don't have to take Methylphenidate to function 100% all the time and as a result feel tremendously anxious 100% all the time. SIGN ME UP.
didgeoridoo 52 minutes ago [-]
Adding guanfacine (Intuniv) to my methylphenidate took the weird anxious-angry edge off. Would be nice to not have to take one med to fix the side effects of the other, though.
fennec-posix 35 minutes ago [-]
Interesting, will check it out. Cheers!
genghisjahn 31 minutes ago [-]
My son takes the methylphenidate / guanfacine combo as well and it’s been a game changer.
hirvi74 30 minutes ago [-]
Any other benefits?
SV_BubbleTime 53 minutes ago [-]
You sure about that math?
fennec-posix 35 minutes ago [-]
I'm honestly not sure about anything man
blinkbat 4 minutes ago [-]
Aw hell no
almost_usual 1 hours ago [-]
Sleep less and sit more. What a species we’ve become.
1 hours ago [-]
madhacker 1 hours ago [-]
"Others are exploring their use for treating sleep apnoea, which is a far more common disorder." CPAP biomedical equipment manufacturer watch out!
livinglist 1 hours ago [-]
24/7 stock market, least sleep needed, most AI piled, I’m very excited!
inigyou 23 minutes ago [-]
Cryptocurrency markets are open 24/7 btw.
Everyone involved in a stock market agrees it's quite useful to have a separation between days, although you could have a 23.5/7 stock market with only half hour day-ends. That's when things like index rebalancing, addition, removal, stock splits occur. You say whoever holds stock X at end of a certain day holds stock Y+Z at the start of the next day (due to a company splitting up) and there's no need to argue about which millisecond a trade occurred. (It's your own damn fault if you were trying to buy the stock in the milliseconds before closing, but some exchanges run a special closing auction with a different algorithm to prevent races). It's also the time you can deploy software, which you can't do during the day. Maybe half an hour is too short for all this stuff. Or maybe it should be a 12 hour window once a week instead.
copperx 3 hours ago [-]
A better modafinil? Sign me up.
EA-3167 2 hours ago [-]
The second I read the print in Nature a bit ago I knew some version would show up here. I swear I’ve met deployed Marines less obsessed with staying awake through chemistry than some people here.
ValdikSS 2 hours ago [-]
Hooray fatal insomnia
acosmism 1 hours ago [-]
wow. now i'm really excited for the future
steele 1 hours ago [-]
[flagged]
Rendered at 03:30:18 GMT+0000 (Coordinated Universal Time) with Vercel.
We have our NeuroLinkBrain Implant plugin to AI agent , so that you can vibe code 24/7 . To maximize shareholder value.
It also helps with non-work stuff that's just not fun to do, such as chores or filing your taxes. It even helps you stick with hobbies you actually enjoy but your brain gets bored of.
I had been looking into orexin agonists (along with other things like H3 autoreceptor antagonists) back when they were just a concept. It’s good to see them finally reaching commercialization. Although they’re not approved by our own (Canadian) regulatory body quite yet.
Now that they’re approved in the US, though, I’m looking very much forward to seeing how these drugs perform in off-label-ish treatment of the various other sleep disorders that I’m sure clinicians will now begin throwing them at.
> IMO the much more likely explanation is that the brain uses contrastive learning somewhere. [...] Instead of using calculus and outer products to calculate derivatives, you feed real data and false data forward through the network and each neuron tracks and trains on the difference.
- when learning on the real examples, just propagate forward
- when learning on the fake examples, first generate them by propagating white noise backward
Everyone involved in a stock market agrees it's quite useful to have a separation between days, although you could have a 23.5/7 stock market with only half hour day-ends. That's when things like index rebalancing, addition, removal, stock splits occur. You say whoever holds stock X at end of a certain day holds stock Y+Z at the start of the next day (due to a company splitting up) and there's no need to argue about which millisecond a trade occurred. (It's your own damn fault if you were trying to buy the stock in the milliseconds before closing, but some exchanges run a special closing auction with a different algorithm to prevent races). It's also the time you can deploy software, which you can't do during the day. Maybe half an hour is too short for all this stuff. Or maybe it should be a 12 hour window once a week instead.